Papers & preprints.

A comparative brain atlas of Mexican cavefish identifies naturally-occurring changes in cellular composition and gene expression

Gallman, K., Ricemeyer, E., Rastogi, A., X. M., Mendez Scolari, E., Duboue, E.R., Rohner, N., Iyer, H., Warren, W.C., Keene, A.C.

bioRxiv (2026)Preprint DOI

Evolved differences in microglial cell biology between surface and cave populations of Astyanax mexicanus

Mendez Scolari, E., Rastogi, A., Amanyi, O.K., Duboue, E.R., Keene, A.C., Iyer, H.

J. Exp. Biol. (2026), accepted manuscriptDOI

Systems Neuroimmunology: Current Bottlenecks, Research Priorities and Future Directions

Iyer, H., Benoist, C., Bilbo, S.D., Boulanger, L.M., Burton, M.D., Daniels, B.P., Deczkowska, A., Flajnik, M.F., Gareau, M.G., Grace, P.M., Irazoqui, J.E., Reynolds, T.L., Rosi, S., Salinas, I., Schaefer, A., Sokol, C.L., Williams, D.W., Klein, R.S.

Nat. Immunol. 26(3):325–329DOI PubMed

Chloride transporter ClC-7 is essential for phagocytic clearance by microglia

Iyer, H., Talbot, W.S.

J. Cell Sci. 137(4): jcs261616DOI PubMed PDF

A lysosomal regulatory circuit essential for the development and function of microglia

Iyer, H., Shen, K., Meireles, A.M., Talbot, W.S.

Sci. Adv. 8(35): eabp8321DOI PubMed PDF

The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity

Gan, L., Seki, A., Shen, K., Iyer, H., Han, K., Hayer, A., Wollman, R., Ge, X., Lin, J.R., Dey, G., Talbot, W.S., Meyer, T.

Nat. Cell Biol. 21(5):614–626DOI PubMed PDF

The lysosomal transcription factor TFEB regulates myelination downstream of the Rag-Ragulator complex

Meireles, A.M., Shen, K., Zoupi, L., Iyer, H., Bouchard, E.L., Williams, A., Talbot, W.S.

Dev. Cell 47(3):319–330DOI PubMed PDF

A premeiotic function for boule in the planarian Schmidtea mediterranea

Iyer, H., Issigonis, M., Sharma, P.P., Extavour, C.G., Newmark, P.A.

Proc. Natl. Acad. Sci. U.S.A. 113(25): E3509–18DOI PubMed PDF

NF-YB regulates spermatogonial stem cell self-renewal and proliferation in the planarian Schmidtea mediterranea

Iyer, H., Collins III, J.J., Newmark, P.A.

PLoS Genet. 12(6): e1006109DOI PubMed PDF

Stem cell progeny contribute to the schistosome host-parasite interface

Collins III, J.J., Wendt, G.R., Iyer, H., Newmark, P.A.

eLife 5: e12473DOI PubMed PDF

Structure guided lead generation for M. tuberculosis thymidylate kinase (Mtb TMK): discovery of 3-cyanopyridone and 1,6-naphthyridin-2-one as potent inhibitors

Naik, M., Raichurkar, A., Bandodkar, B.S., Varun, B.V., Bhat, S., Kalkhambkar, R., Murugan, K., Menon, R., Bhat, J., Paul, B., Iyer, H., et al.

J. Med. Chem. 58(2): 753–66DOI PubMed

Bactericidal activity and mechanism of action of AZD5847, a novel oxazolidinone for treatment of tuberculosis

Balasubramanian, V., Solapure, S., Iyer, H., et al.

Antimicrob. Agents Chemother. 58(1): 495–502DOI PubMed

Adult somatic stem cells in the human parasite, Schistosoma mansoni

Collins III, J.J., Wang, B., Lambrus, B.G., Tharp, M., Iyer, H., Newmark, P.A.

Nature 494: 476–479DOI PubMed PDF

Trisubstituted imidazoles as Mycobacterium tuberculosis glutamine synthetase inhibitors

Gising, J., Nilsson, M.T., Odell, L.R., Yahiaoui, S., Lindh, M., Iyer, H., et al.

J. Med. Chem. 55(6): 2894–8DOI PubMed

Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: an attempt to improve the activity against Mycobacterium tuberculosis

Andaloussi, M., Lindh, M., Björkelid, C., Suresh, S., Wieckowska, A., Iyer, H., et al.

Bioorg. Med. Chem. Lett. 21(18): 5403–7DOI PubMed

Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Andaloussi, M., Henriksson, L.M., Więckowska, A., Lindh, M., Björkelid, C., Larsson, A.M., Suresh, S., Iyer, H., et al.

J. Med. Chem. 54(14): 4964–76DOI PubMed